Yes, Bet365 is safe to use. The sportsbook provides various levels of firewall and other protections and the sportsbook itself is regulated by each of the state gaming regulations Bet365 is legal in.
Where is it Legal to play bet365 in the US? bet365 is legal to players in the US aged 21+ and available to play in 7 states, with Colorado, New Jersey, Iowa, Kentucky, Ohio, Virginia, and Louisiana all accessible to residents in those areas.