The best Three Card Poker strategy suggests that you should play all hands better than Queen, Six and Four, then fold all hands with a lesser value. If you fold, your hand is over and the dealer collects your ante wager and pair of plus wager.
Yes, you can make money playing 3 card poker. It's a mix of skill and luck. Knowing when to bet and when to fold is crucial. Some people have had good wins, but like any gambling, there are no guarantees.